Efficacy, safety, and tolerability of low-dose hormone therapy in managing menopausal symptoms. Academic Article Review uri icon

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  • 563

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  • 573


  • Use of the lowest clinically effective dose of postmenopausal hormone therapy conforms to current recommendations and good clinical practice. Although accumulating evidence demonstrates the efficacy and tolerability of low hormone therapy doses, data about their use are limited by a lack of long-term, randomized studies. This review evaluates current evidence on the efficacy, safety, and tolerability of these preparations and their role in menopausal management.

Digital Object Identifier (DOI)

  • 10.3122/jabfm.2009.05.080134

PubMed Identifier

  • 19734403


  • 22


  • 5


  • Aged
  • Aged, 80 and over
  • Drug Tolerance
  • Drug-Related Side Effects and Adverse Reactions
  • Estrogens
  • Female
  • Hormone Replacement Therapy
  • Humans
  • Menopause
  • Middle Aged
  • Treatment Outcome